RT Article T1 Ethical and Legal Issues in Xenotransplantation JF Bioethics VO 15 IS 5/6 SP 427 OP 442 A1 Melo, Helena A1 Brandão, Cristina A1 Rego, Guilhermina A1 Nunes, Rui LA English PB Wiley-Blackwell YR 2001 UL https://www.ixtheo.de/Record/1781878145 AB In most western countries, there is a ‘human organ shortage’ with waiting lists for the performance of transplantation. In a recent report of the UNOS Ethics Committee it is stated that there are approximately 31,000 potential recipients on waiting lists, but only one fourth of potential donors gave their specific consent. Xenotransplantation – defined as the transplantation of animal cells, tissues or organs into human beings – is associated with particular ethical dilemmas, namely the problems of efficiency and safety of this medical procedure. The objective of this study is to analyse the ethical dilemmas in xenotransplantation with the background of a personal view of moral life. Also, xenotransplantation will be evaluated as far as the legal regulation of transplantation is concerned. In particular, we will consider patients rights in accordance with existing laws on organ and tissue transplantation, animal research and clinical trials. DO 10.1111/1467-8519.00252