Rethinking the oversight conditions of human–animal chimera research

New discoveries are improving the odds of human cells surviving in host animals, prompting regulatory and funding agencies to issue calls for additional layers of ethical oversight for certain types of human-animal chimeras. Of interest are research proposals involving chimeric animals with humanize...

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主要作者: Piotrowska, Monika (Author)
格式: 电子 文件
语言:English
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出版: Wiley-Blackwell [2021]
In: Bioethics
Year: 2021, 卷: 35, 发布: 1, Pages: 98-104
IxTheo Classification:NCH Medical ethics
NCJ Ethics of science
Further subjects:B human–animal chimera
B Public Policy
B Animal welfare
B research ethics
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总结:New discoveries are improving the odds of human cells surviving in host animals, prompting regulatory and funding agencies to issue calls for additional layers of ethical oversight for certain types of human-animal chimeras. Of interest are research proposals involving chimeric animals with humanized brains. But what is motivating the demand for additional oversight? I locate two, not obviously compatible, motivations, each of which provides the justificatory basis for paying special attention to different sets of human-animal chimeras. Surprisingly, the sets of animals that actually get flagged for special scrutiny by research and funding guidelines do not correlate with either of the sets of animals that arise when we think about what is motivating additional oversight. What this shows is that existing research policies and funding guidelines are disconnected from their motivation: the rationale for flagging certain types of human-animal chimeras as requiring special oversight is ignored in execution.
ISSN:1467-8519
Contains:Enthalten in: Bioethics
Persistent identifiers:DOI: 10.1111/bioe.12797