The 3Rs Alone Will Not Reduce Total Animal Experimentation Numbers: A Fundamental Misunderstanding in Need of Correction

Government authorities often view the 3Rs of “replace, reduce, refine” popularized by Russell and Burch as both a regulatory principle and a governance principle aimed at reducing the total amount of animal distress in science. They thus expect that the 3Rs should, in time, result in changes in tota...

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Bibliographic Details
Subtitles:Ethics of Zoonosis in Companion Animals
Main Author: Müller, Nico D. (Author)
Format: Electronic Article
Language:English
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Published: Brill 2023
In: Journal of applied animal ethics research
Year: 2023, Volume: 5, Issue: 2, Pages: 269-284
Further subjects:B transformative governance
B Animal experimentation
B Three Rs
B phase-out
B 3R
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Summary:Government authorities often view the 3Rs of “replace, reduce, refine” popularized by Russell and Burch as both a regulatory principle and a governance principle aimed at reducing the total amount of animal distress in science. They thus expect that the 3Rs should, in time, result in changes in total animal experimentation numbers. Communications by Swiss authorities provide stark examples of this expectation. But the 3Rs do not aim at affecting animal experimentation at the level of total numbers; rather, they focus on study design in the individual case. While the underlying philosophy of the 3Rs indeed included a principle of seeking feasible overall reforms, this notion is completely absent in the 3Rs framework itself. Authorities need to stop treating the 3Rs as a means to reduce total distress and should instead invest resources into developing feasible and effective strategies for transformative governance in animal research.
ISSN:2588-9567
Contains:Enthalten in: Journal of applied animal ethics research
Persistent identifiers:DOI: 10.1163/25889567-bja10042